Replication
Home Up Transcription Translation Replication Review of Processes

 

Replication

The next question to consider is how the DNA allows for growth and reproduction.

Growth

Plants and animals grow by having each cell divide to make two cells. These new cells divide to make more cells and so on. Each new cell must have a new identical set of DNA molecules. The process of making more DNA for the new cells is called replication.

We start the process with an intact double strand of DNA.

Diagram representing a double strand of DNA. [69049.jpg]

Next, the DNA molecule splits and the strands separate.

Diagram representing a split double strand of DNA. [69050.jpg]

With the help of an enzyme, each of the bases is paired up with its corresponding base pair (which, of course, is bonded to a sugar and a phosphate). Adenine gets a thymine, cytosine gets a guanine, and so on. The phosphate of one nucleotide is attached to the sugar (deoxyribose) of the adjacent nucleotide, one after another.

Diagram representing a split double strand of DNA with complentary strand being added. [69051.jpg]

This happens with both strands, and when the process is complete, we have two DNA molecules, one just like the other.

At this point, the cell can divide, and each new cell gets its own set of DNA molecules.

Diagram representing two double strands of DNA. [69052.jpg]

If the newly formed cell stays stays in the same organism this is growth. That organism is now larger than it was.

Cell division is used for both growth and reproduction. If the new cells stay with the existing organism, that is growth. If the new cells split away to form a new organism, that is reproduction (a new geration is formed). In either case, the new cells will have DNA from the original cell. Replication of DNA results in a complete set of DNA for each of the new cells. However, replication of DNA does not always occur when cells divide.

Diagram representing cell division with replication. [celldiv1.gif]

 

New Generations

How is genetic information transferred to a new generation? That depends, in part, on the nature of the plant or animal or other living thing that's being considered. There are a variety of ways this can occur, such as cell division, plant starts, regeneration, or cloning. New cells can be created, with new DNA molecules, in the process earlier described as growth. If the cells separate and form a new organism then that is reproduction rather than growth (or along with growth since things keep happening).

Many creatures, including humans, have two sets of genes (two sets of DNA, shown here as black and red). Diploid is the biological term. When cells in these plants and animals split, they can do so in one of two ways. They can replicate their double set of DNA (growth, shown above) or they can separate their two sets of DNA and make cells with one set of DNA (shown here). Haploid is the biological term. This is done in preparation for reproduction.

Diagram representing cell division without DNA replication. [celldiv2.gif]

In humans and many other species these cells can fuse with cells from another individual to create a new generation with a new double set of genes (DNA) and the growth process resumes.

In some species, however, those cells with just one set of genes will grow and replicate before the fusion occurs. In a sense, they constitute their own generation, but I have digressed.

Diagram representing cell division without DNA replication, followed by fusion of cells. [celldiv3.gif]

Let's get back to the chemistry of these things on the next page.

 

Top of Page

E-mail instructor: Sue Eggling

Clackamas Community College
©2001, 2003 Clackamas Community College, Hal Bender